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Beilstein J. Org. Chem. 2012, 8, 1705–1709, doi:10.3762/bjoc.8.194
Graphical Abstract
Figure 1: Structures of well-known serotonin 5-HT2A agonists 1a,b, 2, and 3, and compounds 4 and 5 reported i...
Scheme 1: Synthesis of arylcyclopropane carboxylic acids from the corresponding cinnamic acids, followed by h...
Scheme 2: Conversion of arylcyclopropane carboxylic acids 10a,b to the amines 4 and 5, and chemical resolutio...
Scheme 3: Chemical resolution of arylcyclopropane carboxylic acid 9 followed by bromination.